Hematopoietic stem cells (HSCs) balance self-renewal and differentiation within the bone marrow, a process that is disrupted under in vitro conditions, posing challenges for ex vivo studies and clinic

NIAID Data Ecosystem00

Retrograde movements determine effective stem cell numbers in intestinal crypts

干细胞转录组学

隐窝细胞异质性分析

Our goal was to compare the transcriptomic profile of lgr5+ high, medium and low cells (corresponding to centre, border and >3 row in crypts) between small and large intestine in mice. We observed dif

NIAID Data Ecosystem20

Effect of the gain-of-function mutation of CXCR4 on the molecular identity of murine Skeletal Stromal/Stem Cells (SSC) and OsteoProgenitor Cells (OPC)

干细胞转录组学

CXCR4趋化因子受体

In order to perform transcriptional analyses of two stromal subsets carrying the gain-of-function mutation of CXCR4, bulk RNA Sequencing (RNA-Seq) was conducted on SSC and OPC sorted from WT (Cxcr4+/+

NIAID Data Ecosystem00

The pattern of gene expression in human CD34(+) stem/progenitor cells

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