Design of fast redox-controlled self-immolative selenium-based cysteine surrogates
收藏NIAID Data Ecosystem2026-05-02 收录
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http://datadryad.org/dataset/doi%253A10.5061%252Fdryad.2bvq83c2q
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资源简介：
The self-immolation of N-selenoethyl cysteine derivatives into cysteine exhibits a strong Thorpe-Ingold effect. Notably, the gem-dimethyl substitution alpha to the selenium atom achieved rate accelerations up to 252-fold, enabling Cys unmasking through C-N bond cleavage within minutes. These investigations offer valuable insights into the mechanism of selenoethyl arm breakdown and new redox-sensitive Cys surrogates.
创建时间：
2025-06-17
