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Integrative Epigenetic Analysis Reveals Therapeutic Targets to the DNA Methyltransferase Inhibitor SGI-110 in Hepatocellular Carcinoma Cells

NIAID Data Ecosystem2026-03-12 收录

肝细胞癌表观遗传学

DNA甲基转移酶抑制剂靶点

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE105067 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2021-07-25

肝细胞癌表观遗传学

差异甲基化分析

A large fraction of HCC in Peru arises in younger, non-cirrhotic patients. Global DNA methylation analysis of the HCC and non-tumor liver (NTL) tissues demostrate a profound overhaul of the developmen

NIAID Data Ecosystem50

DNA methylation data of tumor and non-tumor liver (NTL) tissues from Peruvian patients with hepatocellular carcinoma (HCC).

肝细胞癌表观遗传学

甲基化DNA生物标志物

NIAID Data Ecosystem50

Additional file 8 of Epigenetic inactivation of the 5-methylcytosine RNA methyltransferase NSUN7 is associated with clinical outcome and therapeutic vulnerability in liver cancer

肝细胞癌表观遗传学

RNA甲基化修饰

Supplementary Material 8

Figshare2024-02-15 更新30

Murine HCC development: comparison of wt, krt18+/- and krt18-/- liver tumors hybridized against non-affected wt liver tissue

肝细胞癌表观遗传学

染色体畸变分析

Analysis of the different genotype tumors revealed enhanced chromosomal aberrations in all tumors. The most chromosomal aberrations were found in the krt18-/- tumors. Two-condition experiment: wt (non

NIAID Data Ecosystem50

Integrative analysis of DNA methylation and microRNA expression reveals mechanisms of disparity in hepatocellular carcinoma [RNA-Seq]. Integrative analysis of DNA methylation and microRNA expression reveals mechanisms of disparity in hepatocellular carcinoma [RNA-Seq]

肝细胞癌表观遗传学

种族差异机制

We evaluate the epigenetic mechanisms of racial disparity in HCC through an integrated analysis of DNA methylation, miRNA, and combined regulation of gene expression. Specifically, we acquired DNA met

NIAID Data Ecosystem50

Integrative Epigenetic Analysis Reveals Therapeutic Targets to the DNA Methyltransferase Inhibitor SGI-110 in Hepatocellular Carcinoma Cells

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