Crystal structure of human JMJD2A in complex with compound 14a
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Crystal structure of human JMJD2A in complex with compound 14a Descriptor: 1,2-ETHANEDIOL, 2-(2H-1,2,3-triazol-4-yl)pyridine-4-carboxylic acid, LYSINE-SPECIFIC DEMETHYLASE 4A, ... Authors: Krojer, T, England, K.S, Vollmar, M, Crawley, L, Williams, E, Riesebos, E, Szykowska, A, Burgess-Brown, N, Oppermann, U, Brennan, P.E, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. Deposit date: 2014-06-27 Release date: 2015-06-17 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.23 Å) Cite: Optimisation of a triazolopyridine based histone demethylase inhibitor yields a potent and selective KDM2A (FBXL11) inhibitor. Medchemcomm, 5, 2014
创建时间：
2014-06-27
