BIOCHEMICAL RESPONSES OF THE DREISSENA POLYMORPHA FROM MUNICIPAL POND TO CAFFEINE, MICROPLASTICS, AND HEATING IN SINGLE AND COMBINED EXPOSURES

Pharmaceuticals have become the aquatic pollutants of growing concern. Caffeine is one of the most widely distributed in the surface waters among them. However, the environmentally relevant models of its effect, which include combined exposures with probable confounding factors, are unknown. Microplastics are a suspected vector that influences caffeine bioavailability. The temperature dependence of response, considering the increase of temperature in surface waters, can also be anticipated. The aim of this study was to analyze the input of caffeine, microplastics and elevated temperature into their combined effect on the zebra mussel Dreissena polymorpha (Pallas, 1771).