MORFEEdb, a comprehensive catalog of SNVs affecting upstream ORFs in human 5'UTRs
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MORFEEdb is a database containing all possible single nucleotide variants (SNVs) creating or altering upORFs(upORF-SNVs). MORFEEdb was obtained by first performing a mutational saturation of the 5’UTR of 55 304 transcripts from ~17 000 coding genes where each position in the 5’UTR was in silico mutated withthe 3 alternative nucleotides. The resulting generated VCF files for all transcripts were then annotated with theMORFEE program as described in doi: https://doi.org/10.1101/2024.10.07.616631 The vcf files resulting from the whole genome 5'UTR mutational saturation are included in the results_per_transcripts.zip archive
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Zenodo创建时间：
2025-01-06
