Crystal structure of an extender (SPD28345)-modified human PDK1 complex 2
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Crystal structure of an extender (SPD28345)-modified human PDK1 complex 2 Descriptor: 3-phosphoinositide-dependent protein kinase 1, N-[2-({6-[(2-sulfanylethyl)amino]pyrimidin-4-yl}amino)ethyl]propanamide Authors: Elling, R.A, Penny, D.M, Simmons, R.L, Erlanson, D.A, Romanowski, M.J. Deposit date: 2010-12-09 Release date: 2011-04-20 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Discovery of a potent and highly selective PDK1 inhibitor via fragment-based drug discovery. Bioorg.Med.Chem.Lett., 21, 2011
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2010-12-09
