数据链接：
官方服务：
资源简介：
Overexpressing HTT in neuronal cells.
应用场景：
创建时间：
2019-08-05
相关数据集
Expression data from BAC transgenic mice overexpressing Glo1. Mus musculus
We generated mice with a transgenic BAC on a B6 background. The BAC contains Glo1, and the transgenic mice were found to overexpress Glo1. We performed a microarray on whole-brain RNA of adult mice to
NIAID Data Ecosystem80
TBK1 suppresses mutant HTT induced toxicity and pathology in models of Huntington's disease
Phosphorylation of the N-terminal domain of the Huntingtin (HTT) protein has emerged as an important regulator of its localization, structure, aggregation, clearance, and toxicity. However, validation
NIAID Data Ecosystem40
IL-17 Signaling in Human iPSC-derived Midbrain Neurons in Parkinson's Disease
To determine IL-17-induced global transcriptome changes in midbrain neurons derived from induced pluripotent stem cells (iPSC) from three sporadic Parkinson's disease (PD) patients and three age- and
NIAID Data Ecosystem20
Additional file 12 of TYROBP/DAP12 knockout in Huntington’s disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astrogliosis and motor deterioration
Additional file 12: Table S11. Isolation scheme of the DIA method.
DataCite Commons2024-09-11 更新60
Loss of TDP-43 promotes somatic CAG repeat expansion in Huntington’s disease knock-in mice
RNA was extracted with Trizol reagent, followed by clean-up and DNase I treatment with QIAGEN RNeasy mini kit in accordance with the prescribed protocol provided with the kit. Quality control was perf
Figshare2023-04-17 更新30
