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Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor C-MET in complex with a Pyrrolopyridinepyridone based inhibitor

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Protein Data Bank Japan2024-02-21 更新2026-03-21 收录
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Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor C-MET in complex with a Pyrrolopyridinepyridone based inhibitor Descriptor: 1-(4-fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridine-3-carboxamide, Hepatocyte growth factor receptor Authors: Sack, J. Deposit date: 2008-02-28 Release date: 2008-08-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Discovery of pyrrolopyridine-pyridone based inhibitors of Met kinase: synthesis, X-ray crystallographic analysis, and biological activities. J.Med.Chem., 51, 2008
创建时间:
2008-02-28
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