SMARTA TCR editing

NIAID Data Ecosystem2026-05-02 收录

T细胞工程

CRISPRi基因编辑

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP516235 数据链接链接失效反馈

官方服务：

资源简介：

Generation of artificial TCR sequences by targeting SMARTA TCR alpha or beta with a CRISPR-Cas9 system.

创建时间：

2024-06-27

SWITCHER self-integration into ROSA26 locus

CRISPRi基因编辑

遗传开关设计

We present a novel genetic switch we term SWITCHER based on a floxed wild-type Cre-construct representing a CRISPR-inducible and self-limiting kill switch. By leveraging CRISPR/Cas12a-mediated crRNA-a

NIAID Data Ecosystem40

Additional file 2 of Engineered circular guide RNAs boost CRISPR/Cas12a- and CRISPR/Cas13d-based DNA and RNA editing

CRISPRi基因编辑

核酸序列设计

Additional file 2: Table S1 The sequences of sgRNAs, primers and linkers.

Figshare2023-06-23 更新20

Frequency of INDEL formation in mice using gRNA synthesized from pU6T7 expression vectors.

CRISPRi基因编辑

INDEL突变频率

Frequency of INDEL formation in mice using gRNA synthesized from pU6T7 expression vectors.

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CRISPR RNA-seq from HepG2 (ENCSR194SPW)

CRISPRi基因编辑

肝癌基因表达

Control CRISPR gRNA against no target in HepG2 cells followed by RNA-seq. (NT-BGHcLV07-B) For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov

NIAID Data Ecosystem30

File S2.zip

CRISPRi基因编辑

基因敲入序列分析

Annotated sequence files in .ape format (comparable with Genbank) of knock-ins generated by CRISPR/Cas9-mediated genome editing. Unmodified genomic sequence is also provided.

Figshare2023-03-14 更新20

SMARTA TCR editing

资源简介：

相关数据集