Cdk8 kinase activity regulates transcriptional responses to pathological cardiac hypertrophy [ChIP-seq]

Purpose: The objective of this study was to determine the role of CDK8 kinase activity in hypertrophic transcriptional regulation using an in vitro rat neonatal cardiomyocyte hypertrophy model研究目的：本研究采用体外大鼠新生心肌细胞肥厚模型，旨在明确细胞周期蛋白依赖性激酶8（CDK8）激酶活性在心肌肥厚转录调控中的作用。