Lip@AUR-aptPD-L1 sequencing

The co-incubation system of B16F10 cells and mouse splenocytes was treated with Lip@AUR-aptPD-L1 or Lip@AUR-aptPD-L1+4 Gy IR, afterwards the melanoma cells were extracted and sent to Sangon Biotech (Shanghai) Co., LTD for detection. We have carried out transcriptome sequencing on Lip@AUR-aptPD-L1-treated B16F10 cells to screen the treatment-induced impact on various immune-related signaling pathways, and the KEGG enrichment analysis results immediately suggested that Lip@AUR-aptPD-L1 treatment pronouncedly inhibited the VEGF signaling pathways.