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Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound Saracatinib (AZD0530)

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound Saracatinib (AZD0530) Descriptor: Activin receptor type I, N-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-7-[2-(4-METHYLPIPERAZIN-1-YL)ETHOXY]-5-(TETRAHYDRO-2H-PYRAN-4-YLOXY)QUINAZOLIN-4-AMINE, PHOSPHATE ION, ... Authors: Williams, E.P, Galan Bartual, S, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N. Deposit date: 2020-06-18 Release date: 2020-07-29 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.67 Å) Cite: Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva. JCI Insight, 6, 2021
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2020-06-18
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