Healthy-control steady-state hypoxia-targeted BOLD MRI reference and normative model maps

This dataset contains group-level healthy-control steady-state hypoxia-targeted BOLD reference and normative model maps used in the manuscript “Voxel-wise temporal decomposition of hypoxia-targeted BOLD MRI reveals distinct timing and steady-state response signatures in glioblastoma”.

Maps were derived from 20 healthy controls acquired during controlled isocapnic hypoxia and are provided in MNI space at 1.5 mm isotropic resolution. The steady-state hypoxia-BOLD response is reported in %BOLD/mmHg. The package includes mean and floored standard-deviation maps for conventional atlas-based comparison, beta0 and beta1 maps and floored residual standard-deviation maps for G-adjusted normative modeling, a final validity mask, an n-valid map, metadata, quality-control summary and README.

No individual-subject imaging data, patient imaging data, clinical metadata or identifiable information are included. The dataset is intended to support transparency, methodological reuse and exploratory comparison and should not be interpreted as an age-general clinical normative standard.