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Blockage of STAT3 signaling augments MEK/ERK inhibitor efficacy in esophageal squamous cell carcinoma

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NIAID Data Ecosystem2026-03-13 收录
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Esophageal carcinoma is a common and aggressive malignancy, and its patients have dismal clinical outcomes. There are a few approved targeted therapy agents for ESCC in clinical. Here, we performed a transcriptome (RNA-seq) on ESCC cell line KYSE150 after Trametinib or Trametinib+Stattic treatment, generating the largest RNA-seq dataset in KYSE150 to date.

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2022-01-09
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