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explore the fibrotic mechanisms
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创建时间：
2021-08-14
相关数据集
Copy number variation and expression of exportin-4 associates with severity of fibrosis in metabolic associated fatty liver disease. Copy number variation and expression of exportin-4 associates with severity of fibrosis in metabolic associated fatty liver disease
A duplication in the exportin 4 (XPO4) CNV reduces the expression of hepatic XPO4 leading to maintaining sustained activation of SMAD3/SMAD4 and liver fibrosis. Overall design: We overexpressed Xpo4 i
NIAID Data Ecosystem100
Different effects of rat interferon alpha, beta and gamma on rat hepatic stellate cell proliferation and activation
BACKGROUND: Liver fibrosis is the common sequel of chronic liver diseases. Recent studies have identified hepatic stellate cells as the primary cell type mediating hepatic fibrogenesis. It has been de
PubMed Central2002-04-08 更新20
DataSheet4_Pharmacological mechanisms of Fuzheng Huayu formula for Aristolochic acid I–induced kidney fibrosis through network pharmacology.zip
Renal fibrosis, characterized by the destruction of renal tubules and interstitial capillaries and the accumulation of extracellular matrix proteins, is a common outcome of chronic renal diseases and
NIAID Data Ecosystem10
Data_Sheet_1_Pyruvate kinase M2 modification by a lipid peroxidation byproduct acrolein contributes to kidney fibrosis.docx
Renal fibrosis is a hallmark of diabetic nephropathy (DN) and is characterized by an epithelial-to-mesenchymal transition (EMT) program and aberrant glycolysis. The underlying mechanisms of renal fibr
NIAID Data Ecosystem40
Hepatocyte Nuclear Factor-1β Induces Redifferentiation of Dedifferentiated Tubular Epithelial Cells
Tubular epithelial cells (TECs) can be dedifferentiated by repetitive insults, which activate scar-producing cells generated from interstitial cells such as fibroblasts, leading to the accumulation an
NIAID Data Ecosystem10
