SNP loss-of-heterozygosity (LOH) analysis of tumor and adjacent non-tumor samples in colorectal cancer.

Note: Fifteen reported and four newly identified CRC-susceptibility SNPs were genotyped in tumor and adjacent non-tumor tissues in 705 CRC cases. Only cases with heterozygous genotypes, which provide di-allelic information, were used in the following analysis. Differences in retention of specific alleles were compared using Fisher exact tests.The asterisk indicates significant p-value.