Strain-Specific Proteomics of Fruit-Derived Lactiplantibacillus plantarum

The present study applies a data-independent acquisition (DIA)-based quantitative proteomics workflow using DIA-NN to resolve and compare the whole-cell proteome landscapes of three Lactiplantibacillus strains. By integrating proteomic profiles with existing genomic and metabolomic data, this work aims to identify strain-specific molecular signatures and pathways underlying functional specialization, thereby providing mechanistic insight to support the rational development of targeted probiotic and postbiotic applications.