UCD Cleft primary palate 4.9 Mb candidate region targeted sequencing

Birds of the congenic inbred chicken line UCD Cleft primary palate (UCD cpp.003) carry an autosomal recessive mutation observed as a lethal developmental defect in affected homozygous mutant progeny. This mutation was mapped to a 4.9 Mb region of chromosome 11, and is sequenced in this project in several individuals of the UCD cpp.003 line with the aim of assessing variation linked to the mutation, and ultimately determining the causative element.