Crystal structure of IRAK4 in complex with compound 6
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Crystal structure of IRAK4 in complex with compound 6 Descriptor: 7-ethoxy-1-{[(2S)-5-oxopyrrolidin-2-yl]methoxy}isoquinoline-6-carboxamide, Interleukin-1 receptor-associated kinase 4 Authors: Han, S, Knafels, J.D. Deposit date: 2024-02-22 Release date: 2024-05-01 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.765 Å) Cite: In Retrospect: Root-Cause Analysis of Structure-Activity Relationships in IRAK4 Inhibitor Zimlovisertib (PF-06650833). Acs Med.Chem.Lett., 15, 2024
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2024-02-22
