KRasG12C ligand complex
收藏Protein Data Bank Japan2024-11-20 更新2026-04-19 收录
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https://pdbj.org/mine/summary/7o83
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KRasG12C ligand complex Descriptor: 1-[(7S)-11-chloro-12-(5-methyl-1H-indazol-4-yl)-9-oxa-2,5,15,17-tetrazatetracyclo[8.7.1.02,7.014,18]octadeca-1(17),10,12,14(18),15-pentaen-5-yl]prop-2-en-1-one, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Phillips, C, Breed, J. Deposit date: 2021-04-14 Release date: 2022-04-20 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Discovery of AZD4625, a Covalent Allosteric Inhibitor of the Mutant GTPase KRAS G12C . J.Med.Chem., 65, 2022
创建时间：
2021-04-14
