Crystal Structure of HIV-1 Protease (Q7K, L33I, L63I) in Complex with KNI-10033
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Crystal Structure of HIV-1 Protease (Q7K, L33I, L63I) in Complex with KNI-10033 Descriptor: (4R)-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-3-[(2S,3S)-2-hydroxy-3-({N-[(isoquinolin-5-yloxy)acetyl]-S-methyl- L-cysteinyl}amino)-4-phenylbutanoyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide, GLYCEROL, Protease Authors: Armstrong, A.A, Lafont, V, Kiso, Y, Freire, E, Amzel, L.M. Deposit date: 2007-04-17 Release date: 2007-05-08 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Compensating enthalpic and entropic changes hinder binding affinity optimization. Chem.Biol.Drug Des., 69, 2007
创建时间：
2007-04-17
