Substituted 2-Naphthamidine inhibitors of urokinase

Substituted 2-Naphthamidine inhibitors of urokinase Descriptor: 6-[(Z)-AMINO(IMINO)METHYL]-N-PHENYL-2-NAPHTHAMIDE, SULFATE ION, Urokinase-type plasminogen activator Authors: Wendt, M.D, Rockway, T.W, Geyer, A, McClellan, W, Weitzberg, M, Zhao, X, Mantei, R, Nienaber, V.L, Stewart, K, Klinghofer, V, Giranda, V.L. Deposit date: 2003-03-28 Release date: 2003-09-30 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Identification of Novel Binding Interactions in the Development of Potent, Selective 2-Naphthamidine Inhibitors of Urokinase. Synthesis, Structural Analysis, and SAR of N-Phenyl Amide 6-Substitution. J.Med.Chem., 47, 2004