Crystal Structure of Mycobacterium tuberculosis ThyA in complex with UMP and Pemetrexed
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Crystal Structure of Mycobacterium tuberculosis ThyA in complex with UMP and Pemetrexed Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID, Thymidylate synthase Authors: Reddy, M.C.M, Bruning, J.B, Harshbarger, W, Sacchettini, J.C. Deposit date: 2012-06-25 Release date: 2013-08-07 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of binary and ternary complexes of thymidylate synthase (ThyA) from Mycobacterium tuberculosis: insights into the selectivity and mode of inhibition To be Published
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2012-06-25
