An epigenetic role for maternally inherited piRNAs in transposon silencing
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An epigenetic role for maternally inherited piRNAs in transposon silencing
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2008-11-28
相关数据集
Golden hamster piRNAs are essential for early development and establishment of spermatogonia [hamster_testis.small_RNAseq]
PIWI-associated RNAs (piRNAs) support germline by suppressing retrotransposons and genes. In mice, piRNAs are essential for spermatogenesis but not oogenesis. To test how this applies to other mammals
NIAID Data Ecosystem100
A histone methyltransferase-independent function of PRC2 controls small RNA dynamics during programmed DNA elimination in Paramecium
To limit transposable element (TE) mobilization, most eukaryotes have evolved small RNAs to silence TE activity via homology-dependent mechanisms. Small RNAs, 20-30 nucleotides in length, bind to PIWI
NIAID Data Ecosystem60
Total mRNA and piRNA sequences of delta-mbt-OSCs
Sequencing analyses of total mRNAs in delta-mbt-OSC and OSC (Control). Sequencing analyses of total small RNA, and Piwi-bound, Aub-bound, AGO3-bound piRNAs in delta-mbt-OSCs.
NIAID Data Ecosystem50
Complex interplay between Plant Mobile Domain and Microrchidia silencing pathways. Plant Mobile Domain proteins are required for Microrchidia 1 expression to fulfil transposon silencing
Silencing of transposable elements (TEs) is an essential process to maintain genomic integrity within the cell. In Arabidopsis, together with canonical epigenetic pathways such as DNA methylation and
NIAID Data Ecosystem70
A transposon sensor during epigenetic reprogramming consists of pervasive transcription and endosiRNAs in mouse ES cells [BS-Seq]. Mus musculus
DNA methylation and other repressive epigenetic marks are erased genome-wide in mammalian primordial germ cells (PGCs), the early embryo and in naïve embryonic stem cells (ESCs). This is a critical ph
NIAID Data Ecosystem60
