five

Expression analysis in Carm1 and Pax3 mutant embryos

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https://www.ncbi.nlm.nih.gov/sra/SRP354834
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We have found that Coactivator-associated Arginine Methyltransferase 1 (Carm1) mutant mice have highly penetrant heart defects. These are similar to those found in Pax3 mutant mice and PAX3 is a target of CARM1-mediated methylation. We analyzed gene expression at mid-gestation in both mutant lines. Overall design: RNA was obtained from E12.5 Carm1 and Pax3 mutant embryos and sequenced by a commercial provider (Novogene).
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2022-08-17
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