Effect of the Foxp3 inhibitory peptide P60 on gene array expression of Karpas cell line
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE165260
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By using a phage displayed peptide library we identified peptide P60 as able to bind Foxp3 and inhibit Treg activity. To gain insight into the effect of P60 in Foxp3+ve cells we used Karpas 299 human cell line derived from a human lymphoma with a regulatory T cell profile. Microarray analysis of Karpas cell line incubated with or without P60 peptide was carried out using the Affymetrix human U133 Plus 2.0 array. Two culture condition (absence or presence of P60 peptide in the culture) were studied in two replicates
创建时间：
2024-01-22
