Metabolome analysis of people with type 2 diabetes. Homo sapiens

The aim of this research is to elucidate the genetic predisposition to metabolic syndrome-related diseases such as diabetes and the genetic predisposition to reactivity and side effects of diabetes drugs in Japanese people and to apply this to the prevention of diabetes and personalized medicine. We profiled serum metabolites of persons with T2D with or without diabetic complications using a comprehensive non-targeted metabolomics approach with mass spectrometry. We compared the abundance of the 364 serum metabolites between the persons with T2D with multiple complications (N = 141) and without any complications (N = 159) and calculated the summary statistics. Details of the methods are described in the reference paper.The Data Access Committee of the National Bioscience Database Center (NBDC) approved that this personal data was made published according to the NBDC Guidelines for Human Data Sharing (https://humandbs.biosciencedbc.jp/en/guidelines/data-sharing-guidelines) as the NBDC Research ID hum0372 and the application ID J-DS000220-015.