首页/数据集/A small set of accessible enhancers enables breast cancer cell response tophysiological progestin concentrations. Homo sapiens

A small set of accessible enhancers enables breast cancer cell response tophysiological progestin concentrations. Homo sapiens

NIAID Data Ecosystem2026-03-12 收录

乳腺癌激素响应

增强子调控

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA742223 数据链接链接失效反馈

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资源简介：

A small set of accessible enhancers enables breast cancer cell response tophysiological progestin concentrations

应用场景：

创建时间：

2021-06-29

小细胞肺癌表观遗传学

增强子调控

Additional file 6: Table S5. Super enhancers that are co-occupied by both ASXL3 and BRD4.

Figshare2020-07-16 更新90

PHF13 Activates Enhancers to Promote TGFβ-Induced Epithelial-to-Mesenchymal Transition [RNA-Seq]. PHF13 Activates Enhancers to Promote TGFβ-Induced Epithelial-to-Mesenchymal Transition [RNA-Seq]

上皮-间质转化机制

增强子调控

We investigated the role of PHF13 in TGFβ-induced Epithelial-to-Mesenchymal Transition and found PHF13 is essential for TGFβ-promoted broadest H3K4me3 domains and super-enhancers activation. Overall d

NIAID Data Ecosystem70

FOXA2 suppresses endometrial carcinogenesis and epithelial-mesenchymal transition by regulating enhancer activity

子宫内膜癌

增强子调控

FOXA2 encodes a transcription factor mutated in 10% of endometrial cancers (ECs), with a higher mutation rate in aggressive variants. FOXA2 has essential roles in embryonic and uterine development. Ho

NIAID Data Ecosystem30

WT and DBDmut Breast Cancer Cells

乳腺癌激素响应

性激素受体功能

Estradiol Timecourse of MDA-MB-231ER+ cells containing a WT-ER and DBDmut-ER Cells were treated with 10 nM estradiol in a timecouse ranging from 1 hour to 24 hour treatments.

NIAID Data Ecosystem70

Regulatory Sharing Between Estrogen Receptor α Bound Enhancers [ATAC-seq]

受体信号通路

增强子调控

The human genome encodes an order of magnitude more gene expression enhancers than promoters, suggesting that most genes are regulated by the combined action of multiple enhancers. We have previously

NIAID Data Ecosystem60

A small set of accessible enhancers enables breast cancer cell response tophysiological progestin concentrations. Homo sapiens

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