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Plasmodium vivax SHMT bound with PLP-glycine and GS380

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Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Plasmodium vivax SHMT bound with PLP-glycine and GS380 Descriptor: (4~{S})-6-azanyl-4-[3-(2-cyanophenyl)-5-(trifluoromethyl)phenyl]-3-methyl-4-propan-2-yl-2~{H}-pyrano[2,3-c]pyrazole-5-carbonitrile, CHLORIDE ION, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], ... Authors: Chitnumsub, P, Jaruwat, A, Leartsakulpanich, U, Schwertz, G, Diederich, F. Deposit date: 2017-05-16 Release date: 2017-11-29 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Conformational Aspects in the Design of Inhibitors for Serine Hydroxymethyltransferase (SHMT): Biphenyl, Aryl Sulfonamide, and Aryl Sulfone Motifs Chemistry, 23, 2017

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2017-05-16
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