Enzymerhodopsins represent a recently discovered class of rhodopsins which includes histidine kinase rhodopsin, rhodopsin phosphodiesterases and rhodopsin guanylyl cyclases (RGCs). The regulatory infl
MST1, MST2, MST3, MST4, and YSK1 are conserved members of the mammalian sterile 20-like serine/threonine (MST) family that regulate cellular functions such as proliferation and migration. The MST3 iso
(A) Activities in the biochemical TR-FRET assay using the human FXR-LBD. (B) Activities in Gal4-FXR-LBD fusion cellular reporter assays using mouse (mFXR) and human FXR-LBDs (hFXR). Efficacy is provid
Evidence of physical interaction with the target protein is essential in the development of chemical probes and drugs. The cellular thermal shift assay (CETSA) allows evaluation of drug binding in liv
AMPK inhibitors suppress inflammatory gene expression induced by STING R284S variants. STING R284S variant was expressed in STING-/- MEF cells. RNA was extracted from the MEF cells after treated with