Transcriptional profiling of milk epithelial cells of Kashmiri and Jersey cattle. Transcriptional profiling of milk epithelial cells of Kashmiri and Jersey cattle

The purpose of the present study was to provide a comprehensive transcriptome profiling of mammary gland and to find the key differences in the milk production and related traits between Jersey and Kashmiri cattle. Casein and whey protein genes were found to be highly expressed throughout the lactation cycle. Largest differences in DEGs was reported between D15 and D90 with 1805 genes in Kashmiri cattle and between D15 and D250 with 3392 genes in Jersey cattle. Overall design: The milk samples were collected for epithelial cell isolation from three Kashmiri and three Jersey cattle, representing two study groups. The samples were collected at three time points, day 15 (D15), D90 and D250 of the lactation cycle. There were total three biological replicates per group.