Fisher’s Kappa statistic test p-values for presence of periodic components in protein sequences.

#:representative alleles are shown, all were analyzed.Fisher’s Kappa statistic that tests the null hypothesis that the values in the series are drawn from a normal distribution with variance 1 against the alternative hypothesis that the series has some periodic component. Metrics tested: Asparagine endopeptidase, human cathepsin L and human cathepsin S cut sites, B-cell epitope contact probability, predicted MHC-I and MHC-II binding affinity principal components of amino acids z1, z2, z3.