In vitro expansion of cirrhosis derived liver epithelial cells reveals progenitor-like properties [methylation]. In vitro expansion of cirrhosis derived liver epithelial cells reveals progenitor-like properties [methylation]

By looking at the methylation sites in normal human liver hepatocytes, cholangiocytes, cultured gallbladder organoids, cirrhotic liver organoids and cirrhotic liver cells, we are looking at the cell origin of cirrhotic liver cells. Overall design: To find the relationship between hepatocytes, cholangiocytes and cirrhotic liver cells, we did the bisulphite DNA methylation sequcing.