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Supplementary Table S9 from Recurrent Immunogenic Neoantigens and Their Cognate T-cell Receptors in Treatment-Resistant Metastatic Prostate Cancer

NIAID Data Ecosystem2026-05-10 收录

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单细胞TCR测序分析

数据链接：

https://figshare.com/articles/dataset/Supplementary_Table_S9_from_Recurrent_Immunogenic_Neoantigens_and_Their_Cognate_T-cell_Receptors_in_Treatment-Resistant_Metastatic_Prostate_Cancer/31296483 数据链接链接失效反馈

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资源简介：

Single Cell TCRseq of donor 157 with AR H875Y 10-mer dextramer staining sorted T-cells

应用场景：

创建时间：

2026-02-06

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单细胞TCR测序分析

Differential responses to immune checkpoint inhibitors (ICI) may be attributed to tumor-intrinsic factors or environmental cues; however, these mechanisms cannot fully explain the variable ICI respons

NIAID Data Ecosystem40

Personalized dendritic cell vaccine facilitates the preparation of neoantigen-reactive T cells for adoptive transfer (scTCR-Seq)

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单细胞TCR测序分析

Adoptive cell transfer (ACT) using neoantigen-specific T cells is an effective immunotherapeutic strategy. However, the difficulty in identifying and screening neoantigen-specific T cells limits its w

NIAID Data Ecosystem00

SARS-CoV-2 infection establishes an enhanced, stable, and age-independent CD8+ T cell response against a dominant nucleocapsid epitope using highly restricted TCRs

病毒特异性T细胞免疫

单细胞TCR测序分析

In vitro antigenic challenge identified N222-230 (LLLDRLNQL referred to as LLL) as a dominant epitope that elicited the greatest response (number of responders and magnitude of expansion) from both co

NIAID Data Ecosystem00

Induction of T cell dysfunction and NK-like T cell differentiation in vitro and in patients after CAR T cell treatment [scTCR-seq]

CAR-T细胞功能障碍机制

单细胞TCR测序分析

Chimeric antigen receptor (CAR) T cell therapy has achieved remarkable success in hematological malignancies but remains largely ineffective in solid tumors. A major factor leading to the reduced effi

NIAID Data Ecosystem10

MC38 colorectal tumor cell lines from two different sources display substantial differences in transcriptome, mutanome and neoantigen expression

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肿瘤新抗原免疫识别

The cell line MC38 is a commonly used murine model for colorectal carcinoma. It has a high mutational burden, is sensitive to immune checkpoint immunotherapy and endogenous CD8+ T cell responses again

NIAID Data Ecosystem00

Supplementary Table S9 from Recurrent Immunogenic Neoantigens and Their Cognate T-cell Receptors in Treatment-Resistant Metastatic Prostate Cancer

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