Cryo_EM structure of human FAN1 in complex with 5' flap DNA substrate
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Cryo_EM structure of human FAN1 in complex with 5' flap DNA substrate Descriptor: DNA (continuous), DNA (post-nick), DNA (pre-nick), ... Authors: Jeyasankar, G, Salerno-Kochan, A, Thomsen, M. Deposit date: 2024-03-14 Release date: 2025-01-29 Last modified: 2025-05-28 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: A FAN1 point mutation associated with accelerated Huntington's disease progression alters its PCNA-mediated assembly on DNA. Nat Commun, 16, 2025
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2024-03-14
