Supplemental_tables.pdf
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Supplemental tables. <b>Table S1</b> provides DNA diagnostics of patients with MC4R variants. <b>Table S2</b> provides the cloning and site-directed mutagenesis primers used to create the MC4R primers in the respective expression plasmids. <b>Table S3</b> provides additional characteristics of the 11 pediatric patients with MC4R variants. <b>Table S4</b> provides additional characteristics of the 6 adult patients with MC4R variants. <b>Table S5</b> provides EC50 and Emax obtained from α-MSH and setmelanotide induced cAMP response. <b>Table S6</b> provides EC50 and Emax obtained from α-MSH and setmelanotide induced β-arrestin-2 recruitment. <b>Table S7</b> provides Emax obtained from the quantification of cell surface expression. <b>Table S8 </b>provides Emax obtained from the quantification of total expression. <b>Table S9</b> provides EC50 and Emax obtained from α-MSH and setmelanotide induced ERK activation.
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figshare
创建时间：
2023-12-01
