Exonuclease domain-containing 1 enhances PIWI slicing-triggered piRNA biogenesis via its interaction with TDRD12
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Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline
Piwi proteins and their associated piRNAs are essential in the germline where they repress transposition, regulate translation, and guide epigenetic programming. Little is known, however, about the m
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Epigenetic control of transposable elements in the mouse male germ line by Tex15. Epigenetic control of transposable elements in the mouse male germ line by Tex15
The piRNA biogenesis was evaluated in the mouse testes lacking TEX15. Total small RNAs, MILI-, and MIWI2-associated small RNAs from control (Tex15+/-) and Tex15(-/-) knock-out testes were sequenced. D
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Porin-mediated passage of negamycin across the outer membrane of Escherichia coli
The rise of antimicrobial resistant pathogens calls for new antibacterial treatments, but potent new compounds are scarce. Development of new antibiotics is difficult, especially against Gram-negative
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Desmoglein 2 Is Less Important than Desmoglein 3 for Keratinocyte Cohesion
Desmosomes provide intercellular adhesive strength required for integrity of epithelial and some non-epithelial tissues. Within the epidermis, the cadherin-type adhesion molecules desmoglein (Dsg) 1–4
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PETISCO is a novel protein complex required for 21U RNA biogenesis and embryonic viability
Piwi proteins are important for germ cell development and function in almost all animals studied thus far. These proteins are guided to specific targets, such as transposable elements, by small guide
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