Influenza virus hemagglutinin mutants
收藏国家林业和草原科学数据中心2023-02-12 更新2024-03-07 收录
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The present invention relates to the production of modified influenza viral proteins in plants. More specifically， the present invention relates to producing and increasing influenza virus-like particle (VLP) production in plants， wherein the VLPs comprise the modified influenza viral proteins， such as modified influenza hemagglutinin (HA). The HA protein may comprising an amino acid sequence comprising at least one substitution when compared to a corresponding wildtype amino acid sequence. Further provided are nucleic acid encoding the modified HA protein. Furthermore methods of producing an influenza virus like particle (VLP) and methods of increasing yield of production of an influenza virus like particle (VLP) in a plant， portion of a plant， or a plant cell， are also provided.
提供机构：
国家林业和草原科学数据中心
创建时间：
2023-02-12
