DNA damage response-related parameters and associated Wilcoxon rank-sum tests in platinum-sensitive (A2780) and platinum-resistant (A2780/C30) cell lines.

1cells that are defined as having more than 5 foci per cell, expressed as a fraction of 1002Olive Tail Moment (OTM) values, arbitrary units3AUC values, expressed as (% of γH2AX positive staining cells) x (carboplatin dose)4AUC values (expressed as OTM x carboplatin dose)5t1/2 for γH2AX foci removal, in h6t1/2 values for carboplatin-induced damage repair, in h7apoptosis rates expressed as doses of carboplatin inducing apoptosis (as defined in the Materials and Methods section)8AUC values, expressed as (% of pan-nuclear staining cells) x (carboplatin dose)9Wilcoxon rank-sum tests.DNA damage response-related parameters and associated Wilcoxon rank-sum tests in platinum-sensitive (A2780) and platinum-resistant (A2780/C30) cell lines.