Optimizing the structural features of the dioxygenated benzo lead compound
收藏国家人口健康科学数据中心2026-06-01 收录
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https://www.ncmi.cn/phda/dataDetails.do?id=CSTR:17970.11.A001G.202502.105.V1.0
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资源简介：
We proposed a rational design of spatial configurations to develop dioxygenated derivatives that adhere to specific conformational requirements. This strategy is anticipated to enhance the spatial binding affinity of the inhibitors with FabH, aiming to improve binding affinity while concurrently minimizing off-target effects, thereby further augmenting antibacterial efficacy.
提供机构：
北京蛋白质组研究中心
创建时间：
2024-11-18
