Nuclear Speckles (NS) are phase-separated condensates of protein and RNA whose components dynamically coordinate RNA transcription, splicing, transport and DNA repair. NS, probed largely by imaging st
Nucleus, chromatin, and chromosome organization studies heavily rely on fluorescence microscopy imaging to elucidate the distribution and abundance of structural and regulatory components. Three-dimen
Analysis of X chromosome localization within the nucleus via the three-zone assay. Statistical analysis was done using Student’s t-tests. Statistically significant differences (p<0.05) are highlighted
Number counts based on DAPI-stained embryos (Figure 4 and File S2) are compared to those expected considering preceding mitotic divisions. Note that expected numbers are overestimates from C9 onward,
