Comparison of fixed backbone and coupled moves methods on predicting co-factor binding site sequences.
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Sequence alignments of naturally occurring co-factor binding domains were taken from Pfam and filtered for redundancy. Positions were included in design if they had a side-chain heavy-atom within 6Å of the co-factor ligand and no gaps in the multiple sequence alignment.Comparison of fixed backbone and coupled moves methods on predicting co-factor binding site sequences.
创建时间:
2015-12-03



