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Regulation of KMT2D by PI(3)K/AKT signalling orchestrates oestrogen receptor mediated transcriptional activation in breast cancer

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NIAID Data Ecosystem2026-05-17 收录
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We aim to elucidate the mechanisms of how PI3K inhibition is promoting estrogen receptor (ER) activation and ER dependency in breast cancer. Overall design: Genome-wide analysis of KMT2D upon treatment with the PI3K inhibitor (BYL719).

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2017-09-17
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