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Crystal structure of the human METTL3-METTL14 complex with compound UOZ059b

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Protein Data Bank Japan2024-11-06 更新2026-04-19 收录
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Crystal structure of the human METTL3-METTL14 complex with compound UOZ059b Descriptor: 4-[[(3S)-3-cyclopropyl-2-azaspiro[3.3]heptan-2-yl]methyl]-N-[[(3S)-3-oxidanyl-1-[6-[(phenylmethyl)amino]pyrimidin-4-yl]piperidin-3-yl]methyl]benzamide, ACETATE ION, N6-adenosine-methyltransferase catalytic subunit, ... Authors: Bedi, R.K, Huang, D, Caflisch, A. Deposit date: 2021-05-03 Release date: 2021-10-20 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3 Acs Bio Med Chem Au, 2023

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2021-05-03
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