Gamified Working Memory Intervention Enhances Prefrontal Neurocognitive Plasticity during Aging

Seventy-six older adults were randomly assigned to either the WM intervention group or the active control group. All participants underwent 12 one-hour training sessions spanning six weeks. For each participant, cognitive assessments were completed at pretest, posttest, and six months after the intervention while structural magnetic resonance imaging (MRI) and resting-state functional MRI scans were conducted before and after intervention.