The Human Virome In Children And Its Relationship To Febrile Illness

Viruses are a major cause of febrile illness in children, but the specific cause of viral illnesses is often not determined. This project will define all of the viruses present in normal children and children whose immune systems are suppressed, and will compare the viruses found during periods of febrile illness with the viruses present when the children are well. This information will provide insights into the role of viruses in febrile illness in childhood and will be the basis for future comprehensive studies of the effects of viral infection on the health of children.