miRNA expression data of plasmablastic lymphoma and control group

Plasmablastic lymphoma has been scarcely studied because of its rarity. Transcriptomic studies are crucial to unveil the biology of this lymphoma. In particular, miRNA expression will help to understand the lymphomagenesis of plasmablastic lymphoma. We used microarrays to depict the miRNA expression landscape of plasmablastic lymphoma and to identify miRNAs differentially expressed compared to a control group. RNA was extracted from formalin-fixed paraffin-embedded sections of 66 plasmablastic lymphoma tumors and 14 reactive lymph nodes, as a control group. From total RNA we performed miRNA expression studies using GeneChipTM miRNA 4.0 Array of Affymetrix. miRNA expression profile was compared to the control group to identify miRNAs differentially expressed. We performed an enrichment analysis from miRNAs differentially expressed to identify in which processes these miRNAs are involved.