It is now widely known that C-X3-C motif ligand 1 (CX3CL1) plays an essential part in the process of regulating pro-inflammatory cells migration across a wide range of inflammatory disorders, includin

NIAID Data Ecosystem00

Transcriptomic Profiling of Peripheral Immune Cells in a Trial of Ruxolitinib with Nivolumab for PD1 non-responsive cHL

肿瘤免疫治疗

霍奇金淋巴瘤转录组

Treatment with checkpoint inhibitors is effective in multiple cancer types. However, even in cancers with high response rates such as Hodgkin lymphoma, some patients fail to respond or relapse followi

NIAID Data Ecosystem00

Glycan Mediated Immune Regulation With a Bi-Sialidase Fusion Protein (GLIMMER-01)

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糖基化免疫调节

This is a Phase 1/2, first-in-human, open-label, dose escalation and dose-expansion study of E-602, administered alone and in combination with cemiplimab.

NIAID Data Ecosystem10

A microRNA-regulated transcriptional state defines intratumoral CD8+T cells that respond to immunotherapy. A microRNA-regulated transcriptional state defines intratumoral CD8+T cells that respond to immunotherapy

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CD8T细胞转录状态

Rising rates of advanced-stage colorectal cancer (CRC) and poor survival rates necessitate effective therapeutic options. Immune checkpoint inhibition (ICI), specifically anti-PD-1 therapy, shows pote

NIAID Data Ecosystem00