tcr_beta_synrep_set1_00.txt.bz2

Figshare2020-06-02 更新2026-04-08 收录

T细胞受体序列分析

合成免疫库生成

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Synthetic T cell receptor beta chain repertoire generated using IGoR software. <br><br>Record format: V-gene D-gene J-gene amino-acid-CDR3<br>Where CDR3 contains anchor residues (V-gene Cys, J-gene Phe/Val)<br>

创建时间：

2020-06-02

Machine learning analysis of the T cell receptor repertoire identifies sequence features that predict self-reactivity. Machine learning analysis of the T cell receptor repertoire identifies sequence features that predict self-reactivity

T细胞受体序列分析

反应性预测

The T cell receptor (TCR) determines the specificity and affinity for both foreign and self-peptides presented by MHC. It is established that self-pMHC reactivity impacts T cell function, but it has b

NIAID Data Ecosystem70

Summary of TCRβ CDR3 sequence data.

T细胞受体序列分析

免疫组库测序

The mean number of in-frame, read-through TCRβ CDR3 nucleotide sequence reads obtained from the CD8+CD45RO−CD45RAhiCD62L+ (naïve), CD8+CD45RO+CD45RAlow (memory), CD4+CD45RO−CD45RAhiCD62L+ (naïve) and

NIAID Data Ecosystem50

Targeted reconstruction of T cell receptor sequence from single cell RNA-seq links CDR3 length to T cell differentiation state. Targeted reconstruction of T cell receptor sequence from single cell RNA-seq links CDR3 length to T cell differentiation state

T细胞受体序列分析

T细胞分化

The T cell compartment must contain diversity in both T cell receptor (TCR) repertoire and cell state to provide effective immunity against pathogens. However, it remains unclear how differences in th

NIAID Data Ecosystem40

Pregnancy enables expansion of autoreactive regulatory T cells in an animal model of multiple sclerosis

自身免疫疾病

T细胞受体序列分析

Disease activity of autoimmune disorders such as multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE) is temporarily suppressed by pregnancy. However, whether d

NIAID Data Ecosystem50

Blood samples and associated clonotypes of publically available TCRβ sequences.

T细胞受体序列分析

免疫组库多样性

Male 1 (M1), Male 2 (M2) and Female 1 (F1). *Unseparated, memory and naïve samples 1 and 2 were taken one week apart. Descriptive statistics of the eight samples generated by [14]. This includes the n

NIAID Data Ecosystem40

tcr_beta_synrep_set1_00.txt.bz2

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